Chenodeoxycholic Acid (Highly Pure)

<strong>Chenodeoxycholic Acid (Highly Pure)</strong>_x000D_ <strong>Catalog number:</strong> B2010637_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 25 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 392.57 g/mol_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> molecular tool in the sutdy of various metabolic systems_x000D_ <strong>Storage:</strong> RT_x000D_ <strong>Keywords:</strong> Chenodiol, 5β-Cholanic acid-3α,7α-diol, 3α,7α-Dihydroxy-5β-cholanic acid_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Chenodeoxycholic acid. Lancet. 1978 Apr 15;1(8068):805._x000D_ _x000D_ 2: Shah RA, Kowdley KV. Obeticholic acid for the treatment of nonalcoholic_x000D_ steatohepatitis. Expert Rev Gastroenterol Hepatol. 2020 May;14(5):311-321._x000D_ _x000D_ 3: Chenodeoxycholic acid in the dissolution of gallstones. Nutr Rev. 1976_x000D_ Jan;34(1):20-1._x000D_ _x000D_ 4: Iser JH, Sali A. Chenodeoxycholic_acid: a review of its pharmacological_x000D_ properties and therapeutic use. Drugs. 1981 Feb;21(2):90-119._x000D_ _x000D_ 5: Hofmann AF. Desaturation of bile and cholesterol gallstone dissolution with_x000D_ chenodeoxycholic_acid. Am J Clin Nutr. 1977 Jun;30(6):993-1000._x000D_ _x000D_ 6: Tint GS, Salen G, Shefer S. Effect of ursodeoxycholic acid and_x000D_ chenodeoxycholic acid on cholesterol and bile acid metabolism. Gastroenterology._x000D_ 1986 Oct;91(4):1007-18._x000D_ _x000D_ 7: Fiorucci S, Di Giorgio C, Distrutti E. Obeticholic Acid: An Update of Its_x000D_ Pharmacological Activities in Liver Disorders. Handb Exp Pharmacol._x000D_ 2019;256:283-295._x000D_ _x000D_ 8: Wang H, He Q, Wang G, Xu X, Hao H. FXR modulators for enterohepatic and_x000D_ metabolic diseases. Expert Opin Ther Pat. 2018 Nov;28(11):765-782._x000D_ _x000D_ 9: Ratziu V, Sanyal AJ, Loomba R, Rinella M, Harrison S, Anstee QM, Goodman Z,_x000D_ Bedossa P, MacConell L, Shringarpure R, Shah A, Younossi Z. REGENERATE: Design_x000D_ of a pivotal, randomised, phase 3 study evaluating the safety and efficacy of_x000D_ obeticholic acid in patients with fibrosis due to nonalcoholic steatohepatitis._x000D_ Contemp Clin Trials. 2019 Sep;84:105803._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/79062/">10: Corazziari E, Pozzessere C, Dani S, Piccinni-Leopardi M, Anzini F,_x000D_ Alessandrini A. Chenodeoxycholic acid and diarrhoea. Lancet. 1978 Jul_x000D_ 29;2(8083):266-7. </a>_x000D_ _x000D_ <strong>Products Related to Chenodeoxycholic Acid (Highly Pure)</strong><a href="https://moleculardepot.com/product-category/Chemicals/">: Chemicals</a>