Recombinant Human 5'-nucleotidase/CD73/NT5E Protein (His & AVI Tag)

<strong>Recombinant Human 5'-nucleotidase/CD73/NT5E Protein (His &amp; AVI Tag)</strong>_x000D_ <strong>Catalog number:</strong> B2019133_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 61.04 kDa_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −20°C_x000D_ <strong>Keywords:</strong> CALJA Protein, Human; CD73 Protein, Human; E5NT Protein, Human; eN Protein, Human; eNT Protein, Human; NT Protein, Human; NT5 Protein, Human; NTE Protein, Human_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Yu J, Wang X, Lu Q, Wang J, Li L, Liao X, Zhu W, Lv L, Zhi X, Yu J, Jin Y, Zou Q, Ou Z, Liu X, Zhou P. Extracellular 5'-nucleotidase (CD73) promotes human breast cancer cells growth through AKT/GSK-3β/β-catenin/cyclinD1 signaling pathway Int J Cancer. 2018 Mar 1;142(5):959-967._x000D_ 2: Sowa NA, Voss MK, Zylka MJ. Recombinant ecto-5'-nucleotidase (CD73) has long lasting antinociceptive effects that are dependent on adenosine A1 receptor activation Mol Pain. 2010 Apr 14;6:20._x000D_ 3: Ghoteimi R, Braka A, Rodriguez C, Cros-Perrial E, Duvauchelle V, Uttaro JP, Mathé C, Ménétrier-Caux C, Jordheim LP, Chaloin L, Peyrottes S. Second-Generation CD73 Inhibitors Based on a 4,6-Biaryl-2-thiopyridine Scaffold ChemMedChem. 2023 Apr 3;18(7):e202200594._x000D_ 4: Knapp KM, Zebisch M, Sträter N. Crystallization and preliminary X-ray analysis of the open form of human ecto-5'-nucleotidase (CD73) Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Dec 1;68(Pt 12):1545-9._x000D_ 5: Rahimova R, Fontanel S, Lionne C, Jordheim LP, Peyrottes S, Chaloin L. Identification of allosteric inhibitors of the ecto-5'-nucleotidase (CD73) targeting the dimer interface PLoS Comput Biol. 2018 Jan 29;14(1):e1005943._x000D_ 6: Wu R, Chen Y, Li F, Li W, Zhou H, Yang Y, Pei Z. Effects of CD73 on human colorectal cancer cell growth in vivo and in vitro Oncol Rep. 2016 Mar;35(3):1750-6._x000D_ 7: Hesse J, Rosse MK, Steckel B, Blank-Landeshammer B, Idel S, Reinders Y, Sickmann A, Sträter N, Schrader J. Mono-ADP-ribosylation sites of human CD73 inhibit its adenosine-generating enzymatic activity Purinergic Signal. 2022 Mar;18(1):115-121._x000D_ 8: Ghoteimi R, Nguyen VT, Rahimova R, Grosjean F, Cros-Perrial E, Uttaro JP, Mathé C, Chaloin L, Jordheim LP, Peyrottes S. Synthesis of Substituted 5'-Aminoadenosine Derivatives and Evaluation of Their Inhibitory Potential toward CD73 ChemMedChem. 2019 Aug 6;14(15):1431-1443._x000D_ 9: Nishimoto S, Mizuno T, Takahashi K, Nagano F, Yuzawa Y, Nishiyama A, Osafune K, Hitomi H, Nagamatsu T. CD140b and CD73 are markers for human induced pluripotent stem cell-derived erythropoietin-producing cells FEBS Open Bio. 2020 Mar;10(3):427-433._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/31727245">10: Allard B, Cousineau I, Spring K, Stagg J. Measurement of CD73 enzymatic activity using luminescence-based and colorimetric assays Methods Enzymol. 2019;629:269-289. </a>_x000D_ _x000D_ <strong>Products Related to Recombinant Human 5'-nucleotidase/CD73/NT5E Protein (His &amp; AVI Tag) can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>