CS587
CS587 is a specific inhibitor of CaMK1D with neurocytotoxicity at 10 μM. CS587 modulates the sensitivity of neuronal cells to Aβ oligomer toxicity[1].
Product Specifications
CAS Number
2388506-69-0
UNSPSC
12352005
Target
CaMK
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cs587.html
Purity
98.18
Solubility
DMSO : 100 mg/mL (ultrasonic; warming)
Smiles
NC(C1=CN=C(N2C[C@H](CCC2)N)N=C1NC3=CC(C(C)(C)C#N)=CC(C(C)(C)C#N)=C3)=O
Molecular Formula
C24H30N8O
Molecular Weight
446.55
References & Citations
[1]Grant P, et al. Effects of Specific Inhibitors for CaMK1D on a Primary Neuron Model for Alzheimer's Disease. Molecules. 2021 Dec 18;26 (24) :7669.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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