H-Tyr (3-I) -OH
H-Tyr (3-I) -OH is a potent and effective tyrosine hydroxylase inhibitor. H-Tyr (3-I) -OH is an intermediate in the production of thyroid hormones and has a role as a human or mouse metabolite[1][2].
Product Specifications
CAS Number
70-78-0
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/H-Tyr_3-I_-OH.html
Purity
99.93
Solubility
DMSO : < 1 mg/mL (ultrasonic; warming; heat to 80°C) |H2O : 5 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
O=C(O)[C@@H](N)CC1=CC=C(O)C(I)=C1
Molecular Formula
C9H10INO3
Molecular Weight
307.09
Precautions
H302, H315, H319, H335
References & Citations
[1] D K Ness, et al. Effects of 3-iodo-L-tyrosine, a tyrosine hydroxylase inhibitor, on eye pigmentation and biogenic amines in the planarian, Dugesia dorotocephala. Fundam Appl Toxicol. 1996 Apr;30 (2) :153-61.|[2]GOLDSTEIN M, et al. INHIBITION OF TYROSINE HYDROXYLASE BY 3-IODO-L-TYROSINE. Life Sci (1962) . 1965 Jan;4:261-4.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
Available Sizes
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