Tranexamic acid-13C2,15N

Tranexamic acid-13C2,15N (Cyclocapron-13C2,15N) is the 13C2 and 15N labeled Tranexamic acid. Tranexamic acid is an antifibrinolytic agent that alleviates liver damage and fibrosis in mouse models of chronic bile duct injury[1][2].

Product Specifications

CAS Number

[1292837-95-6]

Product Name Alternative

Cyclocapron-13C2,15N

UNSPSC

12352211

Hazard Statement

H315-H319-H335

Target

Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/tranexamic-acid-13c2-15n.html

Solubility

10 mM in DMSO

Smiles

O[13C]([C@@H]1CC[C@H](CC1)[13CH2][15NH2])=O

Molecular Formula

C6 13C2H15 15NO2

Molecular Weight

160.19

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

References & Citations

[1]Boström J, et al. Potent fibrinolysis inhibitor discovered by shape and electrostatic complementarity to the drug tranexamic acid. J Med Chem. 2013 Apr 25;56 (8) :3273-80.|[2]Joshi N, et al. The antifibrinolytic drug tranexamic acid reduces liver injury and fibrosis in a mouse model of chronic bile duct injury. J Pharmacol Exp Ther. 2014 Jun;349 (3) :383-92.