EMPA

Product Specifications

UNSPSC Description

EMPA is a high-affinity, reversible and selective orexin OX2 receptor antagonist. [3H]EMPA binds to human and rat OX2-HEK293 membranes with KD values of 1.1 and 1.4 nM respectively[1].

Target Antigen

Orexin Receptor (OX Receptor)

Type

Reference compound

Related Pathways

GPCR/G Protein;Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/empa.html

Purity

99.48

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(N(CC)CC1=CC=CN=C1)CN(C2=CC=C(OC)N=C2)S(=O)(C3=CC=CC=C3C)=O

Molecular Weight

454.54

References & Citations

[1]P Malherbe, et al. Biochemical and behavioural characterization of EMPA, a novel high-affinity, selective antagonist for the OX<sub>2</sub> receptor. Br J Pharmacol. 2009 Apr; 156(8): 1326-1341.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-108682/EMPA-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-108682/EMPA-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

680590-49-2

Available Sizes

Curated Selection

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