EMPA

EMPA is a high-affinity, reversible and selective orexin OX2 receptor antagonist. [3H]EMPA binds to human and rat OX2-HEK293 membranes with KD values of 1.1 and 1.4 nM respectively[1].

Product Specifications

CAS Number

[680590-49-2]

UNSPSC

12352005

Hazard Statement

H302

Target

Orexin Receptor (OX Receptor)

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/empa.html

Purity

99.92

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(N(CC)CC1=CC=CN=C1)CN(C2=CC=C(OC)N=C2)S(=O)(C3=CC=CC=C3C)=O

Molecular Formula

C23H26N4O4S

Molecular Weight

454.54

Precautions

H302

References & Citations

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

OX2 Receptor

Available Sizes

Curated Selection

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