EMPA
EMPA is a high-affinity, reversible and selective orexin OX2 receptor antagonist. [3H]EMPA binds to human and rat OX2-HEK293 membranes with KD values of 1.1 and 1.4 nM respectively[1].
Product Specifications
CAS Number
[680590-49-2]
UNSPSC
12352005
Hazard Statement
H302
Target
Orexin Receptor (OX Receptor)
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/empa.html
Purity
99.92
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(N(CC)CC1=CC=CN=C1)CN(C2=CC=C(OC)N=C2)S(=O)(C3=CC=CC=C3C)=O
Molecular Formula
C23H26N4O4S
Molecular Weight
454.54
Precautions
H302
References & Citations
2
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
OX2 Receptor
Available Sizes
Curated Selection
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