EMPA
Product Specifications
UNSPSC Description
EMPA is a high-affinity, reversible and selective orexin OX2 receptor antagonist. [3H]EMPA binds to human and rat OX2-HEK293 membranes with KD values of 1.1 and 1.4 nM respectively[1].
Target Antigen
Orexin Receptor (OX Receptor)
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/empa.html
Purity
99.48
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(N(CC)CC1=CC=CN=C1)CN(C2=CC=C(OC)N=C2)S(=O)(C3=CC=CC=C3C)=O
Molecular Weight
454.54
References & Citations
[1]P Malherbe, et al. Biochemical and behavioural characterization of EMPA, a novel high-affinity, selective antagonist for the OX<sub>2</sub> receptor. Br J Pharmacol. 2009 Apr; 156(8): 1326-1341.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-108682/EMPA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-108682/EMPA-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
680590-49-2
Available Sizes
Curated Selection
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