Boc-Gly-Gly-Phe-Gly-OH (TFA)

Boc-Gly-Gly-Phe-Gly-OH TFA, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC) .

Product Specifications

CAS Number

[2450273-39-7]

UNSPSC

12352209

Hazard Statement

H302, H315, H319, H335

Target

ADC Linker

Type

Peptides

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Neuroscience-Neuromodulation

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/boc-gly-gly-phe-gly-oh-tfa.html

Purity

98.27

Solubility

H2O : 125 mg/mL (ultrasonic)

Smiles

CC(C)(C)OC(NCC(NCC(N[C@H](C(NCC(O)=O)=O)CC1=CC=CC=C1)=O)=O)=O.OC(C(F)(F)F)=O

Molecular Formula

C22H29F3N4O9

Molecular Weight

550.48

Precautions

H302, H315, H319, H335

References & Citations

[1]Dernovics M, et al., Synthesis and application of a Sec2-containing oligopeptide for method evaluation purposes in selenium speciation. Talanta. 2012 Sep 15;99:186-93.