Boc-Gly-Gly-Phe-Gly-OH (TFA)
Boc-Gly-Gly-Phe-Gly-OH TFA, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC) .
Product Specifications
CAS Number
[2450273-39-7]
UNSPSC
12352209
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker
Type
Peptides
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/boc-gly-gly-phe-gly-oh-tfa.html
Purity
98.27
Solubility
H2O : 125 mg/mL (ultrasonic)
Smiles
CC(C)(C)OC(NCC(NCC(N[C@H](C(NCC(O)=O)=O)CC1=CC=CC=C1)=O)=O)=O.OC(C(F)(F)F)=O
Molecular Formula
C22H29F3N4O9
Molecular Weight
550.48
Precautions
H302, H315, H319, H335
References & Citations
[1]Dernovics M, et al., Synthesis and application of a Sec2-containing oligopeptide for method evaluation purposes in selenium speciation. Talanta. 2012 Sep 15;99:186-93.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
Cleavable Linker
Available Sizes
Curated Selection
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