3-Isobutyl-1-methylxanthine

<strong>3-Isobutyl-1-methylxanthine</strong>_x000D_ <strong>Catalog number:</strong> B2017856_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 222.24 g/mol_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> 1-Methyl-3-isobutylxanthine, 3,7-Dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione, 3-Isobutyl-1-methyl-2,6(1H,3H)-purinedione, IBMX_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Geisbuhler TP, Schwager TL, Ervin HD. 3-isobutyl-1-methylxanthine (IBMX) sensitizes cardiac myocytes to anoxia Biochem Pharmacol. 2002 Jun 1;63(11):2055-62._x000D_ 2: Mi Z, Herzer WA, Zhang Y, Jackson EK. 3-isobutyl-1-methylxanthine decreases renal cortical interstitial levels of adenosine and inosine Life Sci. 1994;54(16):277-82._x000D_ 3: Gilbard JP. Treatment of keratoconjunctivitis sicca in rabbits with 3-isobutyl-1-methylxanthine_Arch Ophthalmol. 1994 Dec;112(12):1614-6._x000D_ 4: Hua Y, Ke S, Wang Y, Irwin DM, Zhang S, Wang Z. Prolonged treatment with 3-isobutyl-1-methylxanthine_improves the efficiency of differentiating 3T3-L1 cells into adipocytes Anal Biochem. 2016 Aug 15;507:18-20._x000D_ 5: Srikrishnan T, Parthasarathy R. Studies on modified nucleic acid bases: structure of 3-isobutyl-1-methylxanthine_Acta Crystallogr C. 1988 Dec 15;44 ( Pt 12):2138-40._x000D_ 6: Kivelä M, Tenhu H, Koskelainen A. Binding of 3-isobutyl-1-methylxanthine_into copolymers of N-isopropylacrylamide Eur J Pharm Sci. 2004 Apr;21(5):607-16._x000D_ 7: Mann SC, Andrews PA, Howell SB. Modulation of cis-diamminedichloroplatinum(II) accumulation and sensitivity by forskolin and 3-isobutyl-1-methylxanthine_in sensitive and resistant human ovarian carcinoma cells Int J Cancer. 1991 Jul 30;48(6):866-72._x000D_ 8: Schachter JB, Wolfe BB. 3-Isobutyl-1-methylxanthine_increases alpha-1-adrenergic receptor sensitivity and density in DDT1-MF2 smooth muscle cells J Pharmacol Exp Ther. 1995 Jan;272(1):215-23._x000D_ 9: Wang Z, Bilsky EJ, Wang D, Porreca F, Sadée W. 3-Isobutyl-1-methylxanthine_inhibits basal mu-opioid receptor phosphorylation and reverses acute morphine tolerance and dependence in mice Eur J Pharmacol. 1999 Apr 23;371(1):1-9._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/24212477">10: Huang W, Nagano M, Kang SS, Yanagawa Y, Takahashi Y. Prematurational culture with 3-isobutyl-1-methylxanthine synchronizes meiotic progression of the germinal vesicle stage and improves nuclear maturation and embryonic development in in vitro-grown bovine oocytes J Reprod Dev. 2014 Mar 7;60(1):9-13. </a>_x000D_ _x000D_ <strong>Products Related to 3-Isobutyl-1-methylxanthine can be found at</strong> <a href="https://moleculardepot.com/product-category/Chemicals/"> Chemicals</a>