Fasnall (benzenesulfonate)
Fasnall benzenesulfonate is the benzenesulfonate salt form of Fasnall. Fasnall benzenesulfonate is the inhibitor for fatty acid synthase (FASN) with IC50 of 3.7 μM. Fasnall benzenesulfonate inhibits the proliferation and induces apoptosis in breast cancer cells. Fasnall benzenesulfonate exhibits antitumor efficacy in mice[1].
Product Specifications
CAS Number
2187367-11-7
UNSPSC
12352005
Target
Apoptosis; Fatty Acid Synthase (FASN)
Type
Reference compound
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fasnall-benzenesulfonate.html
Smiles
O=S(O)(C1=CC=CC=C1)=O.CC2=C(C)SC3=NC=NC(NC4CN(CC4)CC5=CC=CC=C5)=C32
Molecular Formula
C25H28N4O3S2
Molecular Weight
496.64
References & Citations
[1]Alwarawrah Y, et al., Fasnall, a Selective FASN Inhibitor, Shows Potent Anti-tumor Activity in the MMTV-Neu Model of HER2 (+) Breast Cancer. Cell Chem Biol. 2016 Jun 23;23 (6) :678-88.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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