(Rac) -Pyrotinib
(Rac) -Pyrotinib ((Rac) -SHR-1258) is the racemic form of Pyrotinib (HY-104065) . Pyrotinib is a potent and selective dual EGFR/HER2 receptor inhibitor.
Product Specifications
CAS Number
[1246089-97-3]
Product Name Alternative
(Rac) -SHR-1258
UNSPSC
12352005
Target
Drug Isomer
Type
Reference compound
Related Pathways
Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rac-pyrotinib.html
Purity
99.29
Solubility
DMSO : 1.81 mg/mL (ultrasonic; warming)
Smiles
O=C(NC1=C(OCC)C=C2N=CC(C#N)=C(NC3=CC=C(OCC4=NC=CC=C4)C(Cl)=C3)C2=C1)/C=C/C5N(C)CCC5
Molecular Formula
C32H31ClN6O3
Molecular Weight
583.08
References & Citations
[1] Li X, et al. Discovery and development of Pyrotinib: A novel irreversible EGFR/HER2 dual tyrosine kinase inhibitor with favorable safety profiles for the treatment of breast cancer. Eur J Pharm Sci. 2017 Jan 21. pii: S0928-0987 (17) 30043-X.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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