(Rac)-Pyrotinib
Product Specifications
UNSPSC Description
(Rac)-Pyrotinib ((Rac)-SHR-1258) is the racemate of Pyrotinib (HY-104065). Pyrotinib is a potent and selective EGFR/HER2 dual inhibitor.
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rac-pyrotinib.html
Purity
99.29
Solubility
DMSO : 1.81 mg/mL (ultrasonic;warming)
Smiles
O=C(NC1=C(OCC)C=C2N=CC(C#N)=C(NC3=CC=C(OCC4=NC=CC=C4)C(Cl)=C3)C2=C1)/C=C/C5N(C)CCC5
Molecular Weight
583.08
References & Citations
[1] Li X, et al. Discovery and development of Pyrotinib: A novel irreversible EGFR/HER2 dual tyrosine kinase inhibitor with favorable safety profiles for the treatment of breast cancer. Eur J Pharm Sci. 2017 Jan 21. pii: S0928-0987(17)30043-X.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-104065A/Rac-Pyrotinib-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-104065A/Rac-Pyrotinib-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1246089-97-3
Available Sizes
Curated Selection
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