Recombinant Human Annexin A1

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

Annexin A1

UniProt

P04083

Reactivity

Human

Target Antigen

Annexin A1

Target

Annexin A1

Type

Protein

Applications

Concentration

Lot Specific

Dilution

Dilute in PBS or medium that is identical to that used in the assay system.

Form

Liquid

Buffer

20 mM Tris

Storage Conditions

Store at 4°C if entire vial will be used within 2-4 weeks. Store at or below - 20°C for longer periods of time. For long term storage, addition of a carrier protein (0.1% HSA or BSA) is recommended. For in vitro investigational use only.

Specificity

Annexin A1

Formulation

Sterile-filtered colorless solution in 20mM Tris-HCl, pH 8.0, 100mM NaCl, 1mM DTT, and 10% glycerol.

Buffer pH

pH 8.0

Target Background

Annexin A1 is a member of the Ca+2- dependent phospholipid binding proteins that are localized on the cytosolic face of the plasma membrane. It inhibits activity of phospholipase A2, binding 2-4 calcium ions with high affinity. Given the involvement of phospholipase A2 in mediating inflammation, prostaglandins, and leukotrienes, Annexin A1 might have potential anti-inflammatory activity.