Practolol
Practolol is a potent and selective β1-adrenergic receptor antagonist. Practolol can be used for the research of cardiac arrhythmias[1][2][3].
Product Specifications
CAS Number
6673-35-4
UNSPSC
12352005
Hazard Statement
H302, H315, H361
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/practolol.html
Purity
99.80
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(NC1=CC=C(OCC(O)CNC(C)C)C=C1)=O
Molecular Formula
C14H22N2O3
Molecular Weight
266.34
Precautions
H302, H315, H361
References & Citations
[1]Iakovidis D, et, al. In vitro activity of RO363, a beta1-adrenoceptor selective agonist. Br J Pharmacol. 1980 Apr;68 (4) :677-85.|[2]Adashi EY, et, al. Stimulation of beta 2-adrenergic responsiveness by follicle-stimulating hormone in rat granulosa cells in vitro and in vivo. Endocrinology. 1981 Jun;108 (6) :2170-8.|[3]Marshall RJ, et, al. Comparative effects of propranolol and practolol in the early stages of experimental canine myocardial infarction. Br J Pharmacol. 1976 Jun;57 (2) :295-303.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
β adrenergic receptor
Available Sizes
Frequently Asked Questions
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