Practolol

Practolol is a potent and selective β1-adrenergic receptor antagonist. Practolol can be used for the research of cardiac arrhythmias[1][2][3].

Product Specifications

CAS Number

[6673-35-4]

UNSPSC

12352005

Hazard Statement

H302, H315, H361

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/practolol.html

Purity

99.80

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(NC1=CC=C(OCC(O)CNC(C)C)C=C1)=O

Molecular Formula

C14H22N2O3

Molecular Weight

266.34

Precautions

H302, H315, H361

References & Citations

[1]Iakovidis D, et, al. In vitro activity of RO363, a beta1-adrenoceptor selective agonist. Br J Pharmacol. 1980 Apr;68 (4) :677-85.|[2]Adashi EY, et, al. Stimulation of beta 2-adrenergic responsiveness by follicle-stimulating hormone in rat granulosa cells in vitro and in vivo. Endocrinology. 1981 Jun;108 (6) :2170-8.|[3]Marshall RJ, et, al. Comparative effects of propranolol and practolol in the early stages of experimental canine myocardial infarction. Br J Pharmacol. 1976 Jun;57 (2) :295-303.