Berbamine
Product Specifications
CAS Number
478-61-5
Type
Natural Products
Related Pathways
Autophagy;NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Berbamine.html
Purity
99.58
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
COC1=C(OC2=CC([C@]3([H])CC(C=C4)=CC=C4O5)=C(CCN3C)C=C2OC)C([C@@]6([H])CC7=CC=C(O)C5=C7)=C(CCN6C)C=C1OC
Molecular Weight
608.72
References & Citations
[1]Liang Y, et al. Berbamine, a novel nuclear factor kappaB inhibitor, inhibits growth and induces apoptosis in human myeloma cells. Acta Pharmacol Sin. 2009 Dec;30(12):1659-65.|[2]Meng Z, et al. Berbamine inhibits the growth of liver cancer cells and cancer-initiating cells by targeting Ca<sup>2+</sup>/calmodulin-dependent protein kinase II. Mol Cancer Ther. 2013 Oct;12(10):2067-77.Biomed Pharmacother. 2024 Aug 15:179:117309.|Chemrxiv. Oct 12, 2021.|Drug Des Devel Ther. 2022 Jan 11;16:129-141.|Mol Pharm. 2022 Oct 21.|Pharmaceuticals. 2024 Nov 25.|PLoS Pathog. 2023 Jan 26;19(1):e1011131.|Cell Stress Chaperones. 2021 Jan 6.|J Ethnopharmacol. 2022 Dec 7;303:116025.|J Periodontol. 2024 Jul 5.|Patent. US20220017867A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Clinical Information
Launched
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR10408891 96 Well
Human Crossover junction endonuclease MUS81 (MUS81) ELISA kit
Sign In for Pricing
View Details