SR 16832
Product Specifications
UNSPSC Description
SR 16832 is a dual site covalent PPARγ inhibitor that acts at orthosteric and allosteric sites[1].
Target Antigen
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/sr-16832.html
Purity
99.89
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC=NC2=CC=C(OC)C=C12)C3=CC([N+]([O-])=O)=CC=C3Cl
Molecular Weight
357.75
References & Citations
[1]Brust R, et al. Modification of the Orthosteric PPARγ Covalent Antagonist Scaffold Yields an Improved Dual-Site Allosteric Inhibitor. ACS Chem Biol. 2017 Apr 21;12(4):969-978.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-112247/SR-16832-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-112247/SR-16832-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2088135-12-8
Available Sizes
Curated Selection
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