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N, S-Bis-Fmoc-Glutathione

N, S-Bis-Fmoc-Glutathione is a potent glyoxalase II inhibitor with a Ki value of 0.75 μM and an IC50 of 2.5 μM[1].

Product Specifications

CAS Number

[149438-56-2]

UNSPSC

12352209

Target

Glyoxalase (GLO)

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/n-s-bis-fmoc-glutathione.html

Purity

99.89

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(OCC1C2=CC=CC=C2C3=CC=CC=C31)SC[C@@H](C(NCC(O)=O)=O)NC(CC[C@@H](C(O)=O)NC(OCC4C5=CC=CC=C5C6=CC=CC=C64)=O)=O

Molecular Formula

C40H37N3O10S

Molecular Weight

751.80

References & Citations

[1]Norton SJ, et al. Inhibitors and inhibition studies of mammalian glyoxalase II activity. Biochem Soc Trans. 1993 May;21 (2) :545-9.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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