Trans-Anethole-d3

Trans-Anethole-d3 is deuterated labeled Trans-Anethole (HY-N0367) . Trans-Anethole ((E) -Anethole) is an orally active phenylpropene derivative found in Foeniculum vulgare that is estrogenic at low concentrations and cytotoxic at high concentrations in tumor cell lines. Trans-Anethole also has anti-aflatoxin, anti-thrombotic and anti-diabetic activities. Trans-Anethole is an important odor component in plants such as fennel, myrtle, liquorice, and camphor[1][2][3][4][5][6][7].

Product Specifications

CAS Number

[444904-67-0]

Product Name Alternative

(E) -Anethole-d3

UNSPSC

12352005

Target

Endogenous Metabolite; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Solubility

10 mM in DMSO

Smiles

[2H]C([2H])([2H])/C=C/C1=CC=C(C=C1)OC

Molecular Formula

C10H9D3O

Molecular Weight

151.22

References & Citations

[1]Tabanca N, et al. Estrogenic activity of isolated compounds and essential oils of Pimpinella species from Turkey, evaluated using a recombinant yeast screen. Planta Med. 2004 Aug;70 (8) :728-35.|[2]Nakagawa Y, et al. Cytotoxic and xenoestrogenic effects via biotransformation of trans-anethole on isolated rat hepatocytes and cultured MCF-7 human breast cancer cells. Biochem Pharmacol. 2003 Jul 1;66 (1) :63-73.|[3]Fahlbusch, et al. "Flavors and Fragrances", Ullmann's Encyclopedia of Industrial Chemistry, Weinheim: Wiley-VCH.|[4]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.