α-Isopropylmalate

α-Isopropylmalate (α-IPM) is the leucine biosynthetic precursor in Yeast[1].

Product Specifications

CAS Number

[3237-44-3]

Product Name Alternative

α-IPM

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Drug Intermediate

Type

Natural Products

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/α-isopropylmalate.html

Purity

99.17

Solubility

H2O : ≥ 250 mg/mL

Smiles

O=C(CC(C(O)=O)(C(C)C)O)O

Molecular Formula

C7H12O5

Molecular Weight

176.17

Precautions

H302, H315, H319, H335

References & Citations

[1]Sze JY, et al. In vitro transcriptional activation by a metabolic intermediate: activation by Leu3 depends on alpha-isopropylmalate. Science. 1992 Nov 13;258 (5085) :1143-5. |[2]Guo H, et al. Regulation of transcription in mammalian cells by yeast Leu3p and externally supplied inducer. FEBS Lett. 1996 Jul 22;390 (2) :191-5.