WNT7A-IN-1 (sodium)
WNT7A-IN-1 sodium (1365-0109), a WNT7A inhibitor, disrupts the protein-protein interaction between WNT7A and its receptor FZD5, resulting in the upregulation of MHC-I expression. WNT7A-IN-1 sodium significantly increases the expression of MHC-I and p-p65, while concurrently reducing the expression of active β-catenin[1]. WNT7A-IN-1 sodium (compound F) is also a photographic sensitizer in the green spectral region[2].
Product Specifications
CAS Number
33628-03-4
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Wnt
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/3-3-bis-3-sulfopropyl-5-5-diphenyl-9-ethyloxacarbocyanine-betaine-sodium.html
Purity
98.05
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=S([O-])(CCC[N+]1=C(/C=C(CC)/C=C2OC3=C(N\2CCCS(=O)(O[Na])=O)C=C(C4=CC=CC=C4)C=C3)OC5=CC=C(C6=CC=CC=C6)C=C51)=O
Molecular Formula
C37H35N2NaO8S2
Molecular Weight
722.80
Precautions
H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Isoform
Wnt7
Available Sizes
Frequently Asked Questions
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