Interleukin-5 (Human, Recombinant)

<strong>Interleukin-5 (Human, Recombinant)</strong>_x000D_ <strong>Catalog number:</strong> B2010312_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Volume/Weight:</strong> 10 ug_x000D_ <strong>pH:</strong> 7.4 upon reconstitution_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Appearance:</strong> Powder_x000D_ <strong>Applications:</strong> highly pure Interleukin-5 (Human, Recombinant) expressed in CHO. This protein acts as a selective activator of human eosinophil function._x000D_ <strong>Storage:</strong> -20C_x000D_ <strong>Keywords:</strong> rHuIL-5; EDF; BCDFII; TRF_x000D_ <strong>Grade:</strong> Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Bagnasco D, Ferrando M, Caminati M, Bragantini A, Puggioni F, Varricchi G,_x000D_ Passalacqua G, Canonica GW. Targeting Interleukin-5 or Interleukin-5Rα: Safety_x000D_ Considerations. Drug Saf. 2017 Jul;40(7):559-570._x000D_ _x000D_ 2: Poblete MJ, Rosenbaum A, Winter M. Anti-interleukin 5 therapy for chronic_x000D_ rhinosinusitis with polyps. Medwave. 2018 Oct 24;18(6):e7301. Spanish, English._x000D_ _x000D_ 3: Takatsu K. Interleukin-5 and IL-5 receptor in health and diseases. Proc Jpn_x000D_ Acad Ser B Phys Biol Sci. 2011;87(8):463-85._x000D_ _x000D_ 4: Giannetti MP, Cardet JC. Interleukin-5 Antagonists Usher in a New Generation_x000D_ of Asthma Therapy. Curr Allergy Asthma Rep. 2016 Nov;16(11):80._x000D_ _x000D_ 5: Kay AB, Klion AD. Anti-interleukin-5 therapy for asthma and hypereosinophilic_x000D_ syndrome. Immunol Allergy Clin North Am. 2004 Nov;24(4):645-66, vii._x000D_ _x000D_ 6: Boggu PR, Kim Y, Jung SH. Discovery of benzimidazole analogs as a novel_x000D_ interleukin 5 inhibitors. Eur J Med Chem. 2019 Nov 1;181:111574._x000D_ _x000D_ 7: Corren J. Inhibition of interleukin 5 for the treatment of eosinophilic_x000D_ diseases. Discov Med. 2012 Apr;13(71):305-12._x000D_ _x000D_ 8: Roboz GJ, Rafii S. Interleukin 5 and the regulation of eosinophil production._x000D_ Curr Opin Hematol. 1999 May;6(3):164-8._x000D_ _x000D_ 9: Karlen S, Mordvinov VA, Sanderson CJ. How is expression of the interleukin 5_x000D_ gene regulated? Immunol Cell Biol. 1996 Apr;74(2):218-23._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/2551778/">10: Miyazaki J, Takaki S, Araki K, Tashiro F, Tominaga A, Takatsu K, Yamamura K._x000D_ Expression vector system based on the chicken beta-actin promoter directs_x000D_ efficient production of interleukin-5. Gene. 1989 Jul 15;79(2):269-77.</a>_x000D_ _x000D_ <strong>Products Related to Interleukin-5 (Human, Recombinant) </strong> <a href="https://moleculardepot.com/product-category/Proteins/">: Proteins</a>