Secnidazole-d6

Secnidazole-d6 is the deuterium labeled Secnidazole. Secnidazole (RP-14539; PM-185184) is an orally active azole antibiotic with a longer half-life than metronidazole (HY-B0318) . Secnidazole is against the vaginosis-associated bacteria and has the potential for bacterial vaginosis research[1].

Product Specifications

CAS Number

[1346603-27-7]

Product Name Alternative

RP-14539-d6; PM-185184-d6

UNSPSC

12352005

Target

Antibiotic; Isotope-Labeled Compounds; Parasite

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Others

Field of Research

Infection

Solubility

10 mM in DMSO

Smiles

[2H]C([2H])([2H])C([2H])(O)C([2H])(N1C([N+]([O-])=O)=CN=C1C)[2H]

Molecular Formula

C7H5D6N3O3

Molecular Weight

191.22

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Petrina MAB, et al. Susceptibility of bacterial vaginosis (BV) -associated bacteria to secnidazole compared to metronidazole, tinidazole and clindamycin. Anaerobe. 2017 Oct;47:115-119.