Recombinant Human Interleukin-2 protein (IL2) (Active)
Product Specifications
Background
Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.
Product Name Alternative
IL-2, TCGF, Aldesleukin
Gene ID
3558
UniProt
P60568
Target
APTSSSTKKT QLQLEHLLLD LQMILNGINN YKNPKLTRML TFKFYMPKKA TELKHLQCLE EELKPLEEVL NLAQSKNFHL RPRDLISNIN VIVLELKGSE TTFMCEYADE TATIVEFLNR
Purification
>97% as determined by SDS-PAGE and HPLC.
Bioactivity
Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine CTLL-2 cells is less than 0.1 ng, ml, corresponding to a specific activity of 1.0 107 IU, mg.
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Calculated Molecular Weight
15.4 kDa
Formulation
0.2 ?m filtered PBS, pH 5.0 , lyophilized
Host or Source
E.Coli
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