Dodecylphosphocholine
Dodecylphosphocholine is a detergent widely utilized in NMR studies of membrane proteins[1][2].
Product Specifications
CAS Number
29557-51-5
UNSPSC
12352211
Hazard Statement
H315, H317, H319, H335, H360
Target
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/dodecylphosphocholine.html
Purity
99.97
Solubility
DMSO : 32.5 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 100 mg/mL (ultrasonic)
Smiles
O=P([O-])(OCC[N+](C)(C)C)OCCCCCCCCCCCC
Molecular Formula
C17H38NO4P
Molecular Weight
351.46
Precautions
H315, H317, H319, H335, H360
References & Citations
[1]de Haas GH, Dijkman R, Ransac S, Verger R. Competitive inhibition of lipolytic enzymes. IV. Structural details of acylamino phospholipid analogues important for the potent inhibitory effects on pancreatic phospholipase A2. Biochim Biophys Acta. 1990;1046 (3) :249-257. |[2]François Dehez, et al. Mitochondrial ADP/ATP Carrier in Dodecylphosphocholine Binds Cardiolipins with Non-native Affinity. Biophys J. 2017 Dec 5;113 (11) :2311-2315.|[3]Sarah D Cady, et al. Specific binding of adamantane drugs and direction of their polar amines in the pore of the influenza M2 transmembrane domain in lipid bilayers and dodecylphosphocholine micelles determined by NMR spectroscopy. J Am Chem Soc. 2011 Mar 30;133 (12) :4274-84.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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