Dodecylphosphocholine

Dodecylphosphocholine is a detergent widely utilized in NMR studies of membrane proteins[1][2].

Product Specifications

CAS Number

[29557-51-5]

UNSPSC

12352211

Hazard Statement

H315, H317, H319, H335, H360

Target

Others

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/dodecylphosphocholine.html

Purity

99.97

Solubility

DMSO : 32.5 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 100 mg/mL (ultrasonic)

Smiles

O=P([O-])(OCC[N+](C)(C)C)OCCCCCCCCCCCC

Molecular Formula

C17H38NO4P

Molecular Weight

351.46

Precautions

H315, H317, H319, H335, H360

References & Citations

[1]de Haas GH, Dijkman R, Ransac S, Verger R. Competitive inhibition of lipolytic enzymes. IV. Structural details of acylamino phospholipid analogues important for the potent inhibitory effects on pancreatic phospholipase A2. Biochim Biophys Acta. 1990;1046 (3) :249-257. |[2]François Dehez, et al. Mitochondrial ADP/ATP Carrier in Dodecylphosphocholine Binds Cardiolipins with Non-native Affinity. Biophys J. 2017 Dec 5;113 (11) :2311-2315.|[3]Sarah D Cady, et al. Specific binding of adamantane drugs and direction of their polar amines in the pore of the influenza M2 transmembrane domain in lipid bilayers and dodecylphosphocholine micelles determined by NMR spectroscopy. J Am Chem Soc. 2011 Mar 30;133 (12) :4274-84.