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Involucrin (Inv, Invo, IVL) (AP)

Product Specifications

Gene Name

[IVL]

NCBI Gene ID

3713

Reactivity

Canine, Human, Porcine

Storage Conditions

May be stored at 4 degree C before opening. DO NOT FREEZE! Stable at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Freezing alkaline phosphatase conjugates will result in a substantial loss of activity.

Specificity

Recognizes human Involucrin. Epitope: codon 421-568 of human Involucrin at ~66-170kD. Species Crossreactivity: Gorilla, Owl monkey, Porcine, and Canine. Does not react with mouse. In Western Blot of cultured human keratinocytes, reacts with a 120kD protein. It stains the involucrin in a variety of sizes: 170kD in MCF-7 cells, a doublet of ~115kD and 150kD in gorilla and owl monkey, 66kD in canine and a doublet of 105kD in porcine.

Other Gene Names

[IVL; IVL]

Short Name

[Involucrin]

Other Product Names

[involucrin; Involucrin; involucrin; involucrin]

NCBI GI Number

44890059

NCBI Accession Number

NP_005538.2

NCBI GB Accession Number

NM_005547.2

Uniprot Accession Number

P07476

Available Sizes

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