Cytokeratin, pan (Pan Keratin) (HRP)

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Recognizes human pan Cytokeratin. Species Crossreactivity: monkey, bovine, canine, rabbit, mouse, rat, chicken. Recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which include CK1 (67kD), CK3 (64kD), CK4 (59kD), CK5 (58kD), CK6 (56kD), CK8 (52kD), CK10 (56.5kD), CK14 (50kD), CK15 (50kD), CK16 (48kD), and CK19 (40kD). Stains cytokeratins present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas.

[keratin, type II cytoskeletal 1b; Keratin, type II cytoskeletal 1b; keratin, type II cytoskeletal 1b; keratin 77; Cytokeratin-1B; CK-1B; Keratin-77; K77; Type-II keratin Kb39]