N-p-trans-Coumaroyltyramine (Standard)
Product Specifications
UNSPSC Description
N-p-trans-Coumaroyltyramine (Standard) is the analytical standard of N-p-trans-Coumaroyltyramine. This product is intended for research and analytical applications. N-p-trans-Coumaroyltyramine is a cinnamoylphenethyl amide isolated from polygonum hyrcanicum, acts as an acetylcholinesterase (AChE) inhibitor with an an IC50 of 122 μM. N-p-trans-Coumaroyltyramine exhibits anti-trypanosomal activity with an IC50 of 13.3 μM for T. brucei rhodesiense[1][2].
Target Antigen
Cholinesterase (ChE); Parasite
Type
Reference Standards
Related Pathways
Anti-infection;Neuronal Signaling
Field of Research
Infection; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/n-p-trans-coumaroyltyramine-standard.html
Smiles
O=C(NCCC1=CC=C(O)C=C1)/C=C/C2=CC=C(O)C=C2
Molecular Weight
283.33
References & Citations
[1]Moradi-Afrapoli F, et al. Cinnamoylphenethyl amides from Polygonum hyrcanicum possess anti-trypanosomal activity. Nat Prod Commun. 2012 Jun;7(6):753-5.|[2]Kim DK, et al. Inhibitory effect of trans-N-p-coumaroyl tryamine from the twigs of Celtis chinensis on the acetylcholinesterase. Arch Pharm Res. 2003 Sep;26(9):735-8.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N2230R/N-p-trans-Coumaroyltyramine-Standard-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N2230R/
CAS Number
36417-86-4
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