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N-p-trans-Coumaroyltyramine (Standard)

N-p-trans-Coumaroyltyramine (Standard) is the analytical standard of N-p-trans-Coumaroyltyramine. This product is intended for research and analytical applications. N-p-trans-Coumaroyltyramine is a natural phenolic amide compound and an inhibitor of AChE (IC50: 122 μM) and α-glucosidase (IC50: 2.7 μM). N-p-trans-Coumaroyltyramine also has anti-trypanosomal activity, with an IC50 of 13.3 µM against T. brucei rhodesiense. N-p-trans-Coumaroyltyramine can be used in the research of diseases such as Alzheimer's disease.

Product Specifications

CAS Number

36417-86-4

UNSPSC

12352005

Target

Cholinesterase (ChE) ; Glycosidase; Parasite; Reference Standards

Type

Reference Standards

Related Pathways

Anti-infection; Metabolic Enzyme/Protease; Neuronal Signaling; Others

Field of Research

Infection; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/n-p-trans-coumaroyltyramine-standard.html

Smiles

O=C(NCCC1=CC=C(O)C=C1)/C=C/C2=CC=C(O)C=C2

Molecular Formula

C17H17NO3

Molecular Weight

283.33

References & Citations

[1]Moradi-Afrapoli F, et al. Cinnamoylphenethyl amides from Polygonum hyrcanicum possess anti-trypanosomal activity. Nat Prod Commun. 2012 Jun;7 (6) :753-5.|[2]Kim DK, et al. Inhibitory effect of trans-N-p-coumaroyl tryamine from the twigs of Celtis chinensis on the acetylcholinesterase. Arch Pharm Res. 2003 Sep;26 (9) :735-8.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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