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N-p-trans-Coumaroyltyramine (Standard)

Product Specifications

UNSPSC Description

N-p-trans-Coumaroyltyramine (Standard) is the analytical standard of N-p-trans-Coumaroyltyramine. This product is intended for research and analytical applications. N-p-trans-Coumaroyltyramine is a cinnamoylphenethyl amide isolated from polygonum hyrcanicum, acts as an acetylcholinesterase (AChE) inhibitor with an an IC50 of 122 μM. N-p-trans-Coumaroyltyramine exhibits anti-trypanosomal activity with an IC50 of 13.3 μM for T. brucei rhodesiense[1][2].

Target Antigen

Cholinesterase (ChE); Parasite

Type

Reference Standards

Related Pathways

Anti-infection;Neuronal Signaling

Field of Research

Infection; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/n-p-trans-coumaroyltyramine-standard.html

Smiles

O=C(NCCC1=CC=C(O)C=C1)/C=C/C2=CC=C(O)C=C2

Molecular Weight

283.33

References & Citations

[1]Moradi-Afrapoli F, et al. Cinnamoylphenethyl amides from Polygonum hyrcanicum possess anti-trypanosomal activity. Nat Prod Commun. 2012 Jun;7(6):753-5.|[2]Kim DK, et al. Inhibitory effect of trans-N-p-coumaroyl tryamine from the twigs of Celtis chinensis on the acetylcholinesterase. Arch Pharm Res. 2003 Sep;26(9):735-8.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-N2230R/N-p-trans-Coumaroyltyramine-Standard-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-N2230R/

CAS Number

36417-86-4

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