4'-Demethylpodophyllotoxone

4'-Demethylpodophyllotoxone is an intermediate product of the biotransformation of Alternaria alternata S-f6. After 4'-Demethylpodophyllotoxone is modified with 4- (2,3,5,6-tetramethylpyrazine-1) (4-TMP), the resulting novel compound can strongly inhibit the growth of human gastric cancer cell line (BGC-823) [1].

Product Specifications

CAS Number

[93780-84-8]

UNSPSC

12352005

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/4-demethylpodophyllotoxone.html

Purity

98.73

Solubility

10 mM in DMSO

Smiles

O=C1[C@]2([H])[C@H](C3=CC(OC)=C(C(OC)=C3)O)C4=CC(OCO5)=C5C=C4C([C@@]2([H])CO1)=O

Molecular Formula

C21H18O8

Molecular Weight

398.36

References & Citations

[1]Zhao W, et al. Manipulation of heterogeneity product in 4′-demethylepipodophyllotoxin biotransformation process by using yeast extract as nitrogen source[J]. Applied microbiology and biotechnology, 2012, 93: 107-115.|[2]Zhao W. et al. Manipulation of heterogeneity product in 4′-demethylepipodophyllotoxin biotransformation process by using yeast extract as nitrogen source[J]. Applied microbiology and biotechnology, 2012, 93: 107-115.