Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

NLRP3-IN-33

NLRP3-IN-33 (Compound 12o) is a blood-brain barrier permeable inhibitor of AChE and BChE, with IC50 values of 1.02 μM and 7.03 μM against hAChE and hBChE respectively. NLRP3-IN-33 possesses antioxidant, anti-inflammatory, and metal chelating activities, making it a potential candidate for research in Alzheimer's disease (AD) [1].

Product Specifications

UNSPSC

12352005

Target

Cholinesterase (ChE) ; Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nlrp3-in-33.html

Solubility

10 mM in DMSO

Smiles

O=C(NCC(NC1=C2C=CC=NC2=C(O)C=C1)=O)/C=C/C3=CC=C(O)C(OC)=C3

Molecular Formula

C21H19N3O5

Molecular Weight

393.39

References & Citations

[1]Singh G, et al. Design, Synthesis, and Biological Evaluation of Ferulic Acid Template-Based Novel Multifunctional Ligands Targeting NLRP3 Inflammasome for the Management of Alzheimer's Disease. ACS Chem Neurosci. 2024;15 (7) :1388-1414.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Recombinant CD45 Antibody
V8395SAF-100UG 100 µg

Recombinant CD45 Antibody

Ask
View Details
Mouse Monoclonal MOX1 Antibody (OTI5B11) [Janelia Fluor 646]
NBP2-72770JF646 0.1 mL

Mouse Monoclonal MOX1 Antibody (OTI5B11) [Janelia Fluor 646]

Ask
View Details
EU 0.1 ml Thin-wall tube
B77204 1000 Tubes/Bag

EU 0.1 ml Thin-wall tube

Ask
View Details
Recombinant Shewanella denitrificans Molybdenum cofactor biosynthesis protein A (moaA)
MBS1284844-01 0.02 mg (E-Coli)

Recombinant Shewanella denitrificans Molybdenum cofactor biosynthesis protein A (moaA)

Ask
View Details
Recombinant Shewanella denitrificans Molybdenum cofactor biosynthesis protein A (moaA)
MBS1284844-02 0.02 mg (Yeast)

Recombinant Shewanella denitrificans Molybdenum cofactor biosynthesis protein A (moaA)

Ask
View Details
Recombinant Shewanella denitrificans Molybdenum cofactor biosynthesis protein A (moaA)
MBS1284844-03 0.1 mg (E-Coli)

Recombinant Shewanella denitrificans Molybdenum cofactor biosynthesis protein A (moaA)

Ask
View Details