Boc-GABA-OH
Boc-GABA-OH is a PROTAC linker which can be used to synthesis UNC6852, an EED-targeted PROTAC[1].
Product Specifications
CAS Number
[57294-38-9]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/boc-gaba-oh.html
Purity
99.14
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(O)CCCNC(OC(C)(C)C)=O
Molecular Formula
C9H17NO4
Molecular Weight
203.24
Precautions
H302, H315, H319, H335
References & Citations
[1]Potjewyd F, et al. Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader. Cell Chem Biol. 2020 Jan 16;27 (1) :47-56.e15.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Alkyl/ether Linkers
Curated Selection
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