Boc-GABA-OH

Boc-GABA-OH is a PROTAC linker which can be used to synthesis UNC6852, an EED-targeted PROTAC[1].

Product Specifications

CAS Number

[57294-38-9]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/boc-gaba-oh.html

Purity

99.14

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(O)CCCNC(OC(C)(C)C)=O

Molecular Formula

C9H17NO4

Molecular Weight

203.24

Precautions

H302, H315, H319, H335

References & Citations

[1]Potjewyd F, et al. Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader. Cell Chem Biol. 2020 Jan 16;27 (1) :47-56.e15.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Alkyl/ether Linkers

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