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Hexaconazole

Hexaconazole is a demethylation enzyme inhibitor and a synthetic fungicide that targets many fungi, especially ascomycetes and basidiomycetes, and it can enhance the activity of SOD and peroxidase. Hexaconazole causes endocrine disorders in zebrafish larvae[1][2][3][4].

Product Specifications

CAS Number

79983-71-4

Product Name Alternative

(-) -Hexaconazol

UNSPSC

12352005

Hazard Statement

H317

Target

Fungal; Reactive Oxygen Species (ROS) ; SOD

Type

Reference compound

Related Pathways

Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Field of Research

Infection; Endocrinology

Assay Protocol

https://www.medchemexpress.com/Hexaconazole.html

Purity

98.11

Solubility

DMSO : ≥ 100 mg/mL|H2O : < 0.1 mg/mL

Smiles

ClC1=CC(Cl)=C(C(CCCC)(O)CN2N=CN=C2)C=C1

Molecular Formula

C14H17Cl2N3O

Molecular Weight

314.21

Precautions

H317

References & Citations

[1]Dubey P et al. Comparative analyses of genotoxicity, oxidative stress and antioxidative defence system under exposure of methyl parathion and hexaconazole in barley (Hordeum vulgare L.) Environ Sci Pollut Res Int. 2015 Dec;22 (24) :19848-59.|[2]Wang Y et al. Monitoring tryptophan metabolism after exposure to hexaconazole and the enantioselective metabolism ofhexaconazole in rat hepatocytes in vitro.&#x0D; J Hazard Mater. 2015 Sep 15;295:9-16.|[3]Feng Zhou, et al. Potential Mechanisms of Hexaconazole Resistance in Fusarium graminearum. Plant Dis. 2024 Oct;108 (10) :3133-3145.|[4]Liang Yu, et al. Thyroid endocrine disruption in zebrafish larvae following exposure to hexaconazole and tebuconazole. Aquat Toxicol. 2013 Aug 15:138-139:35-42.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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