Neopterin-13C5
Neopterin-13C5 (D- (+) -Neopterin-13C5; D-erythro-Neopterin-13C5) is the deuterium labeled Neopterin (HY-W040055) [1]. Neopterin (D- (+) -Neopterin), a catabolic product of guanosine triphosphate (GTM), serves as a marker of cellular immune system activation[2].
Product Specifications
CAS Number
[1217632-04-6]
Product Name Alternative
D- (+) -Neopterin-13C5; D-erythro-Neopterin-13C5
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Endogenous Metabolite; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/neopterin-13c5.html
Purity
97.53
Solubility
10 mM in DMSO
Smiles
O=C1C2=N[13C]([13C@H](O)[13C@H](O)[13CH2]O)=[13CH]NC2=NC(N)=N1
Molecular Formula
C4 13C5H11N5O4
Molecular Weight
258.18
Precautions
H315, H319, H335
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
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ERBB2, phosphorylated (Y877) (ERBB2, HER2, MLN19, NEU, NGL, Receptor tyrosine-protein kinase erbB-2, Metastatic lymph node gene 19 protein, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Tyrosine kinase-type cell surface receptor HER2, p185erbB2, CD340)
Immunoglobulin-Like Transcript 2 (LT2, Leukocyte Immunoglobulin-like Receptor Subfamily B Member 1, LIR-1, Leukocyte Immunoglobulin-like Receptor 1, CD85 Antigen-like Family Member J, ILT-2, Monocyte/Macrophage Immunoglobulin-like Receptor 7, MIR-7, CD85j, LILRB1, LIR1, MIR7) (HRP)