N- (Azido-PEG3) -N- (PEG2-NH-Boc) -PEG3-acid
N- (Azido-PEG3) -N- (PEG2-NH-Boc) -PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N- (Azido-PEG3) -N- (PEG2-NH-Boc) -PEG3-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Product Specifications
CAS Number
[2183440-74-4]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-azido-peg3-n-peg2-nh-boc-peg3-acid.html
Purity
98.07
Solubility
10 mM in DMSO
Smiles
O=C(OC(C)(C)C)NCCOCCOCCC(N(CCOCCOCCOCCN=[N+]=[N-])CCOCCOCCOCCC(O)=O)=O
Molecular Formula
C29H55N5O13
Molecular Weight
681.77
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
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