CGI 560
CGI 560 is an inhibitor for Bruton's tyrosine kinase (BTK) with an IC50 of 400 nM.
Product Specifications
CAS Number
845269-74-1
UNSPSC
12352005
Target
Btk
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cgi-560.html
Smiles
O=C(C1=CC=C(C(C)(C)C)C=C1)NC2=CC(C3=CN4C(C(NC5=CC=CC=C5)=N3)=NC=C4)=CC=C2
Molecular Formula
C29H27N5O
Molecular Weight
461.56
References & Citations
[1]Lv J, et al., Development of Bruton's Tyrosine Kinase Inhibitors for Rheumatoid Arthritis. Curr Med Chem. 2018;25 (42) :5847-5859.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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