5′-Nucleotidase Human

<strong>5‚Ä≤-Nucleotidase Human</strong>_x000D_ <strong>Catalog number:</strong> B2019479_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 6 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> ~61¬†kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> RT_x000D_ <strong>Keywords:</strong> CD73, NT5E, ecto-5‚Ä≤-nucleotidase_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MŒ©-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Maiuolo J, Oppedisano F, Gratteri S, Muscoli C, Mollace V. Regulation of uric acid metabolism and excretion Int J Cardiol. 2016 Jun 15;213:8-14._x000D_ 2: Goyal NA. Inclusion Body Myositis Continuum (Minneap Minn). 2022 Dec 1;28(6):1663-1677._x000D_ 3: Bai A, Robson S. Beyond ecto-nucleotidase: CD39 defines human Th17 cells with CD161 Purinergic Signal. 2015 Sep;11(3):317-9._x000D_ 4: Jacoberger-Foissac C, Cousineau I, Bareche Y, Allard D, Chrobak P, Allard B, Pommey S, Messaoudi N, McNicoll Y, Soucy G, Koseoglu S, Masia R, Lake AC, Seo H, Eeles CB, Rohatgi N, Robson SC, Turcotte S, Haibe-Kains B, Stagg J. CD73 Inhibits cGAS-STING and Cooperates with CD39 to Promote Pancreatic Cancer Cancer Immunol Res. 2023 Jan 3;11(1):56-71._x000D_ 5: Itoh R. IMP-GMP 5'-nucleotidase Comp Biochem Physiol B. 1993 May;105(1):13-9._x000D_ 6: Zhu Y, Banerjee A, Xie P, Ivanov AA, Uddin A, Jiao Q, Chi JJ, Zeng L, Lee JY, Xue Y, Lu X, Cristofanilli M, Gradishar WJ, Henry CJ, Gillespie TW, Bhave MA, Kalinsky K, Fu H, Bahar I, Zhang B, Wan Y. Pharmacological suppression of the OTUD4/CD73 proteolytic axis revives antitumor immunity against immune-suppressive breast cancers J Clin Invest. 2024 Mar 26;134(10):e176390._x000D_ 7: Roh M, Wainwright DA, Wu JD, Wan Y, Zhang B. Targeting CD73 to augment cancer immunotherapy Curr Opin Pharmacol. 2020 Aug;53:66-76._x000D_ 8: Allard D, Chrobak P, Allard B, Messaoudi N, Stagg J. Targeting the CD73-adenosine axis in immuno-oncology Immunol Lett. 2019 Jan;205:31-39._x000D_ 9: Soh KY, Loh JMS, Proft T. Cell wall-anchored 5'-nucleotidases in Gram-positive cocci Mol Microbiol. 2020 Apr;113(4):691-698._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/38747288">10: Marchese E, Demehri S. Posttranslational protein modifications as gatekeepers of cancer immunogenicity J Clin Invest. 2024 May 15;134(10):e180914. </a>_x000D_ _x000D_ <strong>Products Related to 5‚Ä≤-Nucleotidase Human can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>