KLF10 Recombinant Rabbit Monoclonal Antibody [JE34-09]
Selected Variant
HA722324
Size: 100 µL
Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'. Plays a role in the regulation of the circadian clock; binds to the GC box sequence in the promoter of the core clock component ARTNL/BMAL1 and represses its transcriptional activity. Regulates the circadian expression of genes involved in lipogenesis, gluconeogenesis, and glycolysis in the liver. Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis (By similarity). May play a role in the cell cycle regulation.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
KLF10, TIEG, TIEG1
Swiss Prot
Q13118 Human, O89091 Mouse, O08876 Rat
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human KLF10 aa 1-100 / 480.
Isotype
IgG
Clone
JE34-09
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB
Positive Control
HepG2 cell lysate, Jurkat cell lysate, K-562 cell lysate, mouse lung tissue lysate, mouse testis tissue lysate, rat thymus tissue lysate.
Concentration
1 mg/mL
Dilution
WB: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 53 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Price
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