CBP/p300 ligand 2
CBP/p300 ligand 2 is a ligand for target protein for PROTAC of dCBP-1. dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP[1].
Product Specifications
CAS Number
[2484741-78-6]
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cbp-p300-ligand-2.html
Purity
99.39
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O=C(N1CCC(N(C2CCNCC2)N=C3N4CCCC5=C4C=C(C(F)F)C(C6=CN(C)N=C6)=C5)=C3C1)NC
Molecular Formula
C27H34F2N8O
Molecular Weight
524.61
Precautions
H315, H319, H320
References & Citations
[1]Jing Liu, et al. Cyclic-amp response element binding protein (cbp) and/or adenoviral e1a binding protein of 300 kda (p300) degradation compounds and methods of use. O2020173440A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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