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TPH2 Recombinant Rabbit Monoclonal Antibody [PSH04-89]

Tryptophan hydroxylase 2 (TPH2) is an isozyme of tryptophan hydroxylase found in vertebrates. In humans, TPH2 is primarily expressed in the serotonergic neurons of the brain, with the highest expression in the raphe nucleus of the midbrain. Until the discovery of TPH2 in 2003, serotonin levels in the central nervous system were believed to be regulated by serotonin synthesis in peripheral tissues, in which tryptophan hydroxylase is the dominant form.

Product Specifications

Product Name Alternative

MGC138871 antibody ADHD7 antibody FLJ37295 antibody MGC138872 antibody Neuronal tryptophan hydroxylase antibody NTPH antibody TPH 2 antibody Tph2 antibody TPH2_HUMAN antibody Tryptophan 5-hydroxylase 2 antibody Tryptophan 5-monooxygenase 2 antibody Tryptophan hydroxylase 2 antibody

Abbreviation

TPH2, NTPH

Swiss Prot

Q8CGV2 Mouse, Q8CGU9 Rat

Cellular Locus

Cytosol, neuron projection.

Host

Rabbit

Species Reactivity

Mouse,Rat

Immunogen

Recombinant protein.

Isotype

IgG

Clone

PSH04-89

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, IHC-Fr, IP

Positive Control

Mouse hippocampus tissue lysate, mouse brain tissue lysate, rat brain tissue lysate, rat hippocampus tissue lysate, mouse midbrain tissue, mouse cerebrum tissue, rat cerebrum tissue, mouse brain (raphe nucleus) tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000-1:2,000 ;IHC-P: 1:500 ;IHC-Fr: 1:200 ;IP: 1-2μg/sample

Purity

Protein A affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 56 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

CAS Number

9000-83-3

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