Human Gamma Thrombin

<strong>Human Gamma Thrombin</strong>_x000D_ <strong>Catalog number:</strong> B2013733_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 12 kDa_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> Human Gamma Thrombin_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Davie EW, Kulman JD. An overview of the structure and function of thrombin Semin Thromb Hemost. 2006 Apr;32 Suppl 1:3-15._x000D_ 2: Jandrot-Perrus M, Guillin MC, Nurden AT. Human gamma-thrombin: lack of correlation between a platelet functional response and glycoprotein V hydrolysis Thromb Haemost. 1987 Oct 28;58(3):915-20._x000D_ 3: Naldini A, Morena E, Filippi I, Pucci A, Bucci M, Cirino G, Carraro F. Thrombin inhibits IFN-gamma production in human peripheral blood mononuclear cells by promoting a Th2 profile J Interferon Cytokine Res. 2006 Nov;26(11):793-9._x000D_ 4: Brower MS, Walz DA, Garry KE, Fenton JW 2nd. Human neutrophil elastase alters human alpha_thrombin function: limited proteolysis near the gamma-cleavage site results in decreased fibrinogen clotting and platelet-stimulatory activity Blood. 1987 Mar;69(3):813-9._x000D_ 5: Bezeaud A, Denninger MH, Guillin MC. Interaction of human alpha_thrombin and gamma_thrombin with antithrombin III, protein C and thrombomodulin Eur J Biochem. 1985 Dec 16;153(3):491-6._x000D_ 6: Rydel TJ, Yin M, Padmanabhan KP, Blankenship DT, Cardin AD, Correa PE, Fenton JW 2nd, Tulinsky A. Crystallographic structure of human gamma_thrombin J Biol Chem. 1994 Sep 2;269(35):22000-6._x000D_ 7: Soslau G, Prest PJ, Class R, Jost M, Mathews L. Inhibition of gamma_thrombin-induced human platelet aggregation by histone H1subtypes and H1.3 fragments Platelets. 2009 Aug;20(5):349-56._x000D_ 8: Witting JI, Miller TM, Fenton JW 2nd. Human alpha- and gamma_thrombin specificity with tripeptide p-nitroanalide substrates under physiologically relevant conditions Thromb Res. 1987 May 15;46(4):567-74._x000D_ 9: Bishop PD, Lewis KB, Schultz J, Walker KM. Comparison of recombinant human_ thrombin_ and plasma-derived human alpha_thrombin Semin Thromb Hemost. 2006 Apr;32 Suppl 1:86-97._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/21782041">10: Huntington JA. Thrombin plasticity Biochim Biophys Acta. 2012 Jan;1824(1):246-52. </a>_x000D_ _x000D_ <strong>Products Related to Human Gamma Thrombin can be found at</strong> <a href="https://moleculardepot.com/product-category/Enzymes/"> Enzymes</a>