5-Aminolevulinic acid-d2 (hydrochloride)

5-Aminolevulinic acid-d2 (hydrochloride) is deuterium labeled 5-Aminolevulinic acid (hydrochloride) .

Product Specifications

CAS Number

[187237-35-0]

Product Name Alternative

5-ALA-d2 (hydrochloride) ; δ-Aminolevulinic acid-d2 (hydrochloride) ; 5-Amino-4-oxopentanoic acid-d2 (hydrochloride)

UNSPSC

12352211

Target

Apoptosis; Autophagy; Endogenous Metabolite; Isotope-Labeled Compounds; Mitophagy

Type

Isotope-Labeled Compounds

Related Pathways

Apoptosis; Autophagy; Metabolic Enzyme/Protease; Others

Applications

Cancer-programmed cell death

Field of Research

Metabolic Disease; Cancer

Purity

91.20

Solubility

DMSO : 12.5 mg/mL (ultrasonic)

Smiles

OC(C([2H])([2H])CC(CN)=O)=O.Cl

Molecular Formula

C5H8D2ClNO3

Molecular Weight

169.60

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Eyupoglu, I.Y., et al., Improving the extent of malignant glioma resection by dual intraoperative visualization approach. PLoS One, 2012. 7 (9) : p. e44885.|[3]Stummer, W., et al., Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial. Lancet Oncol, 2006. 7 (5) : p. 392-401.