TIM 3 Recombinant Rabbit Monoclonal Antibody [PSH07-75]
Hepatitis A virus cellular receptor 2 (HAVCR2), also known as T-cell immunoglobulin and mucin-domain containing-3 (TIM-3), is a protein that in humans is encoded by the HAVCR2 (TIM-3)gene. HAVCR2 was first described in 2002 as a cell surface molecule expressed on IFNγ producing CD4+ Th1 and CD8+ Tc1 cells. Later, the expression was detected in Th17 cells, regulatory T-cells, and innate immune cells (dendritic cells, NK cells, monocytes, macrophages). HAVCR2 receptor is a regulator of the immune response.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
HAVCR2, TIM3, TIMD3
Swiss Prot
Q8TDQ0 Human
Cellular Locus
Membrane, Cell junction, Cell membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within human TIM 3 aa 1-223.
Isotype
IgG
Clone
PSH07-75
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB
Positive Control
RPMI 8226 cell lysate, HUT 102 cell lysate.
Concentration
1 mg/mL
Dilution
WB: 1:4,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 33 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
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