Anti-inflammatory agent 88

Anti-inflammatory agent 88 (compound 6) is a carbazole derivative with anti-inflammatory activity found in marine Streptomyces. It exerts its anti-inflammatory effect by inhibiting pro-inflammatory factors and enhancing the expression of anti-inflammatory factors in the Myd88/Nf-κB pathway. Anti-inflammatory agent 88 can be used for the development of anti-inflammatory drugs[1].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

MyD88; NF-κB

Type

Reference compound

Related Pathways

Immunology/Inflammation; NF-κB

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-inflammatory-agent-88.html

Smiles

COC1=C(C2=C(NC3=C(C=CC=C32)O)C=C1)Br

Molecular Formula

C13H10BrNO2

Molecular Weight

292.13

References & Citations

[1]Yan P, et al. Bromine/Sulfur-Substituted 9 H-Carbazoles Produced by the Marine-Derived Streptomyces sp. OUCMDZ-5511 upon NaBr Exposure[J]. Journal of Natural Products, 2024.