Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

GM-60186

GM-60186 is a 5-HT receptor 2B (HTR2B) inhibitor with an IC50 of 257 nM. GM-60186 significantly inhibits colorectal cancer proliferation and migration[1].

Product Specifications

UNSPSC

12352005

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/gm-60186.html

Concentration

10mM

Purity

99.34

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

COC1=CC=CC(CCC2=CC=CC=C2OCC(O)CN3CCC(C4=NOC5=C4C=CC(F)=C5)CC3)=C1

Molecular Formula

C30H33FN2O4

Molecular Weight

504.59

References & Citations

[1]Jeong-Yun Lee, et al. Inhibition of HTR2B-mediated serotonin signaling in colorectal cancer suppresses tumor growth through ERK signaling. Biomed Pharmacother. 2024 Oct:179:117428.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

α-1 microglobulin

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Cytokeratin 7 (KRT7/1198), CF647 conjugate, 0.1mg/mL
BNC471198-100 1x 100 µL

Cytokeratin 7 (KRT7/1198), CF647 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
ARF5 Rabbit Monoclonal Antibody [Clone ID: 23GB3635]
TA424484S 20 µL

ARF5 Rabbit Monoclonal Antibody [Clone ID: 23GB3635]

Sign In for Pricing
View Details
Cytokeratin 8 (K8/383), CF488A conjugate, 0.1mg/mL
BNC880383-100 1x 100 µL

Cytokeratin 8 (K8/383), CF488A conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Superior Prime Broth™
0111 500 g

Superior Prime Broth™

Sign In for Pricing
View Details
MIR642 Human qPCR Primer Pair (MI0003657)
HP300553 200 Reactions

MIR642 Human qPCR Primer Pair (MI0003657)

Sign In for Pricing
View Details
Recombinant Human FLT1 Protein (Fc Tag)
PKSH033445-01 10 µg

Recombinant Human FLT1 Protein (Fc Tag)

Sign In for Pricing
View Details