Pipecolic acid
Pipecolic acid is a metabolite of lysine and an important precursor for many useful microbial secondary metabolites. Pipecolic acid slows ferroptosis in diabetic retinopathy by inhibiting the YAP-GPX4 signaling pathway. In addition, Pipecolic acid can be used as a diagnostic marker for pyridoxine-dependent epilepsy[1][2][3].
Product Specifications
CAS Number
535-75-1
UNSPSC
12352200
Hazard Statement
H315, H319, H335
Target
Endogenous Metabolite; Ferroptosis; Glutathione Peroxidase; YAP
Type
Biochemical Assay Reagents
Related Pathways
Apoptosis; Metabolic Enzyme/Protease; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Metabolic Disease; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Pipecolic_acid.html
Purity
99.92
Solubility
H2O : 50 mg/mL (ultrasonic)
Smiles
O=C(O)C1CCCCN1
Molecular Formula
C6H11NO2
Molecular Weight
129.16
Precautions
H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Isoform
GPX4; Human Endogenous Metabolite; Microbial Metabolite
Available Sizes
Frequently Asked Questions
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