BMS-566394
BMS-566394 is a potent inhibitor of tumor necrosis factor-α (TNF-α) converting enzyme (TACE) that helps reduce the production of TNF-α, thereby alleviating inflammation and immune-mediated diseases and can be used in the study of inflammatory and autoimmune diseases[1].
Product Specifications
CAS Number
503166-51-6
UNSPSC
12352005
Target
TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Inflammation/Immunology; Others
Assay Protocol
https://www.medchemexpress.com/bms-566394.html
Smiles
O=C(N[C@H](CCOC1)[C@H]1C(NO)=O)C(C=C2)=CC=C2CN3C(C(F)(F)F)=NC4=CC=CC=C34
Molecular Formula
C22H21F3N4O4
Molecular Weight
462.42
References & Citations
[1]Sengupta P, et al. Synthesis, preliminary biological evaluation and molecular modeling of some new heterocyclic inhibitors of TACE[J]. European journal of medicinal chemistry, 2011, 46 (11) : 5549-5555.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
HP231154 200 Reactions
C6orf52 Human qPCR Primer Pair (NM_001145020)
Sign In for Pricing
View Details 
LC402834 20 µg
Scramblase 1 (PLSCR1) (NM_021105) Human Over-expression Lysate
Sign In for Pricing
View Details 
TRC-D216265-2.5MG 2.5 mg
5-Dodecanoylaminofluorescein Di-b-D-galactopyranoside
Sign In for Pricing
View Details 
